Pierluca Buonfrate studia singing pop con Cinzia Baldana e a seguire canto jazz con Fabrizia Barresi, tecnica lirica con Carlo di Giacomo, pianoforte con Pierpaolo Principato e percussioni con Sergio Quarta. Frequenta seminari con Sheila Jordan, Jay Clayton, Mark Murphy, Bob Stoloff, Judy Niemack, Carl Anderson, Jo Estill, Miles Griffith, Dean Bowman.
He has taught singing since 1994 in several music schools in Rome and since 1996 he is professor and coordinator of the chair of jazz singing at Saint Louis College of Music.
He was vocal coach in the 2018-2019 edition of "Amici" (Mediaset).
Since 2000, he sang in Renzo Arbore's orchestra "Swing Maniacs", participating in Tours, recordings and television broadcasts.
In 2001, he was a finalist for the "Massimo Urbani" award.
Chorister in many R.A.I. broadcasts from 2000 to 2010. He worked in commercials, film and fiction soundtracks, in voice-over singing and in radio Jingles.
Leader of several jazz formations under his name, he collaborated with the most important musicians of the Roman scene.
He participated, in the Big Band "Jazz Company" of M° Gabriele Comeglio, in the theatrical tour (in various editions from 2005 to 2010) "Ciao Frankie" by Massimo Lopez, of which he has been vocal coach since 2005.
In October 2014 he was invited with Lino Patruno to perform in New Orleans in a tribute to Louis Prima.
For the Erasmus+ project, he teaches jazz singing courses at the "Metropolia" Conservatory in Helsinki, in London at West London University, at the Royal Academy in Aalborg (DN), "HoGent School of Arts" in Gent (Belgium), and participates as an educator at the Summer Camp P.I.S.U. of the University of Pristina (Kosovo).
In 2017, he participated in the "Italian jazz on the Road", a project with which he performed in Finland, Denmark and Belgium with a repertoire of Italian music and original arrangements.
He collaborated with the writer Luciano De Crescenzo on a tour to present his books, singing in the "Big Night Jive", swing orchestra with which he recorded two CD's: "Jumpin Jive" and "Las Vegas Style".
He collaborated with M° Gianfranco Lombardi in the realization of his project on the neapolitan classical songs.
He collaborated with drummer Agostino Marangolo on his CD "Day by day".
He is a member of Mameli Voices, an Italian swing vocal quartet with whom he recorded the album "Love in Portofino".
In 2018, he recorded his solo work "Words" (AlfaMusic), a CD of original jazz compositions inspired by Miles Davis; after presenting it in February 2019 at the Alexanderplatz in Rome, he is invited by the Antwerp Conservatory to perform it at the "Jazz in T'Mas" festival.